While most people think that poor diet is ultimately the cause of the obesity and diabetes epidemics, there remains great debate on what is the critical part of the diet that is responsible. Is it just too many calories in general, or is there a specific food? Is it too many carbs, too much fat, the wrong kinds of fats (like seed oils) or too little protein, or is it just all of the junk food? Here we take the various hypotheses and show that all may be correct, but that they may fall together in one overall hypothesis that has fructose at the center, with carbs having primarily a role in driving craving and metabolic complications, while fat is providing the high levels of calories that drive weight gain.
Weblink for the National Library of Medicine paper here: https://pubmed.ncbi.nlm.nih.gov/37846155/
For a request for the paper, please email richard.johnson@ucdenver.edu
